Structure-Activity Relationship and Molecular Binding Analysis of HS-176 Lead Scaffold
National Institutes of Health · United States
Time Left to Bid
Awarded
Basic information
- Reference number
- 75N93025C00040
- Issuing organization
- National Institutes of Health · Find award history →
- Government level
- Federal
- Solicitation type
- Other
- Title
- Structure-Activity Relationship and Molecular Binding Analysis of HS-176 Lead Scaffold
- Source
- USASpending (Federal)
- Source ID
- usa-75N93025C00040
Details
- Location
- United States
Summary
This contract involves conducting structure-activity relationship (SAR) studies, molecular binding analysis, and metabolism evaluation of the HS-176 lead scaffold to guide development of more potent and drug-like analogs. The work includes prioritization of lead analogs through in vitro efficacy screening to identify the most promising candidates for further development.
Description
PERFORM A STRUCTURE ACTIVITY RELATIONSHIP (SAR), MOLECULAR BINDING AND METABOLISM OF THE LEAD SCAFFOLD (HS-176) TO GUIDE THE DEVELOPMENT OF MORE POTENT AND DRUG LIKE ANALOGS, AND PRIORITIZATION OF LEAD ANALOGS THROUGH IN VITRO EFFICACY SCREENING AND Awarded to: EYDIS BIO, INC. Agency: Department of Health and Human Services Sub-agency: National Institutes of Health Award type: DEFINITIVE CONTRACT
Dates
- Publication
- 2025/09/29 12:00:00 AM UTC
- Closing date
- 2026/10/31 12:00:00 AM UTC
Estimated value
$500K USD
Classification
Normalized category